Solanaceae is known as nightshade or potato family consisting of 102 genera and 2500 species.Most of solanaceous members contain Tropane and Glycoalkaloids.Present work observes seven genera of solanaceae as alkaloid positive members of which Solanum xanthocarpum and Nicotiana plumbaginifolia show highest alkaloid value Maximum number of alkaloid containing parts found in Solanum xanthocarpum. Plants species of solanaceae are enumerated with their medicinal property and uses.