Clinical Observation on Uric Acid-decreasing Formula Treating Chronic Kidney Disease with Hyperuricemia

Objective:To observe the effect of uric acid-decreasing formula treating chronic kidney disease with hyperuricemia and the influence of changes of uric acid in serum on kidney functions.Methods:64 cases were divided into treatment and control groups with 32 cases in each group.The treatment group was given treatment based on syndrome differentiation based on western medicine treatment.The control group was only given western medicine.Both were treated for 8 weeks.SUA,Bun,Scr,eGFR,Alb,TC,TG and U-TP were observed.Results:For treating hyperuricemia,the effective rate in treatment group was superior to that in control group(59.37% vs 28.13%,P0.05);For treating kidney function,the total effective rate in treatment group was superior to that in control group(84.37% vs 53.12%,P0.05).The decrease of SUA in treatment group was superior to that in control group(P0.05).mAfter treatment,Scr level was decreased and eGFR level was increased in treatment group,which had significance compared with control group(P0.05).nAfter treatment,U-TP in treatment group had significance both in intragroup and intergroup comparisons(P0.05),other indexes had no significance(P0.05).The decrease of Scr in effective cases was superior to that in control group(P0.05).Conclusion:Uric acid-decreasing formula can decrease the SUA level in patients with chronic kidney disease combined with hyperuricemia.The decrease of SUA can help to improve the kidney functions.