Experimental study on ninety days feeding experiment of Morinda citrifolia powder.

[Objective]To assess the safety of Morinda citrifolia after long-term oral administration and provide the basis of the toxicology safety for exploiting it as function food.[Methods]The test samples were added to foundation animal feeds by using the proportion of 1.7%,3.3% and 8.0%,which was equivalent to 50,100 and 240 times of body recommendation intake respectively.Ninety days rat feeding trial was detected by oral administration.[Results]There were no significant differences in the changes of weight,food-intake,ingesta availability,hematology,blood biochemistry,organ weigh,organ and body ratio in test group and in the control group.No-observed-adverse-effect level was 8.00g/kg weight,which was equivalent to 240 times of body recommendation intake.[Conclusion]Long-term oral administration of Morinda citrifolia powder is safe according to the dose of experimental empirical study.