Analysis of Bone Mineral Density of Lumbar Spine in Middle-old-aged Female with Quantitative Computed Tomography

Objective To explore the clinical value and the difference of bone mineral density(BMD) in every vertebra of lumbar spine in middle old-aged Chinese female with quantitative computed tomography (QCT).Methods The BMD in every vertebra of lumbar spine was investigated by QCT in 725 healthy females aged from 35 to 98 years. They were divided into groups every five years.The BMD in vertebra of lumbar spine (L 1～L 4) were measured by QCT and the groups tested for significant differences,using SPSS10.0 software for the analysis.Results Lumbar spine (L 1～L 4) BMD declined with aging. The bone quantity was predominantly declined in group of 50 to 54 years (Ρ0.01). In addition, in L 1, it was shown that bone decline BMD was predomiaantly from 45 years to 64 years (Ρ0.05).Conclusion There is significant BMD decline with aging and it is difference in vertebrae of lumbar spine (L 1～L 4) in middle old-aged Chinese female, especially for L 1,it is important to use QCT technique in BMD measurement and in diagnosis of osteoporosis.