The Uptake of Nitrogen and Ammonia Assimilation by Saccharomyces Cerevisiae

Saccharomyces cerevisiae is able to use a wide variety of nitrogen sources for growth. The first step is that most nitrogen sources is uptake by specific permeates. The nest step is the degradation of the nitrogen source via ammonia assimilation. Ammonia plays a central role as intermediate between degradative and biosynthetic pathways. The role of ammonia assimilation is at the level of enzyme activity, translation, and transcription. This review describes the mechanism of the uptake of nitrogen sources and ammonia assimilation, and also the research on the metabolic engineering of the ammonia assimilation.