Development of a mild and efficient protocol for the protection and O-alkylation of allyl alcohols

An efficient, pyridine-free protocol has been developed for the protection of 3°-allyl alcohol of oxindole using a mild base of potassium carbonate under microwave irradiation conditions. The methodology has been tested with a variety of substrates and protecting group reagents, which provides a clean and good yield of desired products within a short reaction time.