吞噬作用
药物输送
材料科学
药品
巨噬细胞
细胞
纳米技术
药理学
医学
免疫学
生物
体外
生物化学
作者
Nishit Doshi,Albert J. Swiston,Jonathan B. Gilbert,M.L. Alcaraz,Robert E. Cohen,Michael F. Rubner,Samir Mitragotri
标识
DOI:10.1002/adma.201004074
摘要
Macrophages are recruited at the diseased site in several pathological conditions. Here, we describe a novel method of utilizing their unique properties for targeted drug delivery. Cellular backpacks are designed that ride on macrophage surfaces without affecting cell functions or getting internalized. These backpacks can be used as multimodal therapeutic and diagnostic agents.
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