生物
序列(生物学)
序列标志
职位(财务)
集合(抽象数据类型)
共识序列
Logos圣经软件
自由序列分析
k-mer公司
序列比对
遗传学
基序列
DNA测序
计算机科学
肽序列
DNA
基因
财务
经济
程序设计语言
操作系统
作者
Thomas D. Schneider,Robert M. Stephens
标识
DOI:10.1093/nar/18.20.6097
摘要
A graphical method is presented for displaying the patterns in a set of aligned sequences. The characters representing the sequence are stacked on top of each other for each position in the aligned sequences. The height of each letter is made proportional to its frequency, and the letters are sorted so the most common one is on top. The height of the entire stack is then adjusted to signify the information content of the sequences at that position. From these 'sequence logos', one can determine not only the consensus sequence but also the relative frequency of bases and the information content (measured in bits) at every position in a site or sequence. The logo displays both significant residues and subtle sequence patterns.
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