医学
骨质疏松症
安慰剂
荟萃分析
股骨颈
物理疗法
伯格天平
随机对照试验
骨矿物
平衡(能力)
内科学
病理
替代医学
作者
Siyi Zhu,Yi Li,Liqiong Wang,Jinming Huang,Kangping Song,Xu Gan,Xi Xiang,Chengqi He,Lin Yang
出处
期刊:IEEE Transactions on Neural Systems and Rehabilitation Engineering
[Institute of Electrical and Electronics Engineers]
日期:2022-01-01
卷期号:30: 321-328
被引量:2
标识
DOI:10.1109/tnsre.2022.3149483
摘要
Little is known about the effect of pulsed electromagnetic fields (PEMFs) as an option for preventing osteoporosis. This study sought to investigate the effectiveness of PEMFs for the management of primary osteoporosis in older adults. We searched databases from the inception to date to target trials examining the effects of PEMFs compared to placebo or sham or other agents for the management of primary osteoporosis for a meta-analysis using random effects model. Eight trials including 411 participants were included. PEMFs was non-inferior to conventional pharmacological agents and exercise respectively in preventing the decline of Bone Mineral Density (BMD) at the lumbar (MD 8.76; CI -9.64 to 27.16 and MD 1.33; CI -2.73 to 5.39) and femur neck (MD 0.04; CI -1.09 to 1.16 and MD 1.50; CI -0.26 to 3.26), and significantly improving balance function measured by Berg Balance Scale (BBS) (MD 0.91; CI 0.32 to 1.49) and Timed Up and Go test (MD -3.61; CI -6.37 to -0.85), directly after intervention. The similar trends were observed in BMD and BBS at 12- and 24-weeks follow-up from baseline. PEMFs had positive effects non-inferior to first-line treatment on BMD and better over placebo on balance function in older adults with primary osteoporosis, but with moderate to very low certainty evidence and short-term follow-ups. There is a need for high-quality randomised controlled trials evaluating PEMFs for the management of primary osteoporosis.
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