医学
血浆置换术
单采
免疫吸附
体外
重症监护医学
肾移植
治疗性血浆置换
透析
随机对照试验
白细胞清除术
肾
免疫学
内科学
抗体
血小板
干细胞
生物
川地34
遗传学
作者
Yiyuan Chen,Xin Sun,Weichao Huang,Fang-Fang He,Chun Zhang
出处
期刊:Renal Failure
[Informa]
日期:2022-06-19
卷期号:44 (1): 842-857
被引量:9
标识
DOI:10.1080/0886022x.2022.2073892
摘要
Besides conventional medical therapies, therapeutic apheresis has become an important adjunctive or alternative therapeutic option to immunosuppressive agents for primary or secondary kidney diseases and kidney transplantation. The available therapeutic apheresis techniques used in kidney diseases, including plasma exchange, double-filtration plasmapheresis, immunoadsorption, and low-density lipoprotein apheresis. Plasma exchange is still the leading extracorporeal therapy. Recently, growing evidence supports the potential benefits of double-filtration plasmapheresis and immunoadsorption for more specific and effective clearance of pathogenic antibodies with fewer side effects. However, more randomized controlled trials are still needed. Low-density lipoprotein apheresis is also an important supplementary therapy used in patients with recurrent focal segmental glomerulosclerosis. This review collects the latest evidence from recent studies, focuses on the specific advantages and disadvantages of these techniques, and compares the discrepancy among them to determine the optimal therapeutic regimens for certain kidney diseases.
科研通智能强力驱动
Strongly Powered by AbleSci AI