医学
贾纳斯激酶
STAT蛋白
信号转导
肺
免疫系统
炎症
激酶
机制(生物学)
激活剂(遗传学)
免疫学
针灸科
斯达
PI3K/AKT/mTOR通路
蛋白激酶A
蛋白激酶C
车站3
Janus激酶2
药理学
癌症研究
生物信息学
JAK-STAT信号通路
平衡
转录因子
磷脂酰肌醇
缺血
细胞信号
临床试验
作者
Xiaoyu Wang,Rui-Shi Shen,Huifang Tang,Hua-Shun Cui
出处
期刊:PubMed
日期:2025-11-25
卷期号:50 (11): 1333-1338
标识
DOI:10.13702/j.1000-0607.20241282
摘要
Acute lung injury (ALI) is a severe and critical condition, characterized by high incidence and mortality rates, posing significant challenges to current treatment strategies. In recent years, the application of acupuncture in treating ALI has attracted widespread attention. This paper focuses on the role of acupuncture in treating ALI and systematically summarizes the mechanism by which acupuncture inhibits excessive inflammatory responses and maintains immune homeostasis through the regulation of pro-inflammatory signaling pathways such as mitogen-activated protein kinase (MAPK), nuclear factor kappa B (NF-κB), phosphatidylinositol 3-kinase / protein kinase B (PI3K/Akt), janus kinase / signal transducer and activator of transcription (JAK/STAT). Furthermore, it explores the specific role of acupuncture in reducing lung inflammation and tissue damage, providing a scientific basis and reference for further study of its anti-inflammatory mechanism and application in ALI.
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