肿瘤微环境
转录组
计算生物学
肿瘤异质性
生物
肿瘤细胞
计算机科学
癌症研究
基因
癌症
遗传学
基因表达
作者
Ana C. Anderson,Itai Yanai,Lucy R. Yates,Linghua Wang,Alexander Swarbrick,Peter K. Sorger,Sandro Santagata,Wolf‐Herman Fridman,Qiang Gao,Livnat Jerby,Benjamin Izar,Lulu Shang,Xiang Zhang
出处
期刊：Cancer Cell
[Elsevier]
日期：2022-09-01
卷期号：40 (9): 895-900
被引量：14
标识
DOI：10.1016/j.ccell.2022.08.021
摘要
Spatial transcriptomics, with other spatial technologies, has enabled scientists to dissect the organization and interaction of different cell types within the tumor microenvironment. We asked experts to discuss some aspects of this technology from revealing the tumor microenvironment and heterogeneity, to tracking tumor evolution, to guiding tumor therapy, to current technical challenges. Spatial transcriptomics, with other spatial technologies, has enabled scientists to dissect the organization and interaction of different cell types within the tumor microenvironment. We asked experts to discuss some aspects of this technology from revealing the tumor microenvironment and heterogeneity, to tracking tumor evolution, to guiding tumor therapy, to current technical challenges.
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