Multifunctional PHC Bandage for Accelerated Wound Healing in Movable Parts

Wound healing in movable parts poses challenges owing to frequent activities, leading to delayed recovery and heightened susceptibility to bacterial infections and inflammation. Although hydrogel-based dressings have been explored, their therapeutic effectiveness is limited by poor resistance to stimuli and low mechanical strength. Here, we present a novel multifunctional PHC bandage that prevents bacterial infection and capitalizes on the inherent mobility of the affected area to expedite the wound-healing process. A PHC bandage was fabricated by incorporating photothermal copper bismuth sulfide (Cu₃BiS₃) nanomaterials into piezoelectric and pyroelectric polyvinylidene fluoride (PVDF). Upon exposure to alternating near-infrared light, the embedded Cu₃BiS₃ generated localized heat, activated PVDF, and induced the production of abundant reactive oxygen species for bacterial inactivation. Furthermore, continuous movement of the wound area triggers the PVDF to generate a sustained electrical field, promoting cell migration and proliferation to facilitate wound healing. The wound healing rate of PHC was 13.17 ± 2.09% higher than medical gauze. The robust encapsulation of PVDF ensured secure containment of the loaded Cu₃BiS₃ nanoparticles, improving the biocompatibility and sustainable utilization of this innovative wound dressing. This innovative design offers a promising and effective solution for improving wound healing in movable parts, potentially revolutionizing wound care technology.