Cardiac medication non‐adherence: the elephant in the room

Internal Medicine JournalEarly View Letter to the Editor Cardiac medication non-adherence: the elephant in the room Kristoffer K. Ralota, Kristoffer K. Ralota orcid.org/0009-0002-8261-6222 Department of Cardiology, Peninsula Health, Melbourne, Victoria, AustraliaSearch for more papers by this authorMisha Dagan, Misha Dagan Department of Cardiology, Peninsula Health, Melbourne, Victoria, AustraliaSearch for more papers by this authorJohn Lee, John Lee Department of Cardiology, Peninsula Health, Melbourne, Victoria, AustraliaSearch for more papers by this authorVardhaman Gowda, Vardhaman Gowda Department of Cardiology, Peninsula Health, Melbourne, Victoria, AustraliaSearch for more papers by this authorJamie Layland, Jamie Layland Department of Cardiology, Peninsula Health, Melbourne, Victoria, AustraliaSearch for more papers by this author Kristoffer K. Ralota, Kristoffer K. Ralota orcid.org/0009-0002-8261-6222 Department of Cardiology, Peninsula Health, Melbourne, Victoria, AustraliaSearch for more papers by this authorMisha Dagan, Misha Dagan Department of Cardiology, Peninsula Health, Melbourne, Victoria, AustraliaSearch for more papers by this authorJohn Lee, John Lee Department of Cardiology, Peninsula Health, Melbourne, Victoria, AustraliaSearch for more papers by this authorVardhaman Gowda, Vardhaman Gowda Department of Cardiology, Peninsula Health, Melbourne, Victoria, AustraliaSearch for more papers by this authorJamie Layland, Jamie Layland Department of Cardiology, Peninsula Health, Melbourne, Victoria, AustraliaSearch for more papers by this author First published: 01 April 2025 https://doi.org/10.1111/imj.70042Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookxLinkedInRedditWechat No abstract is available for this article. References 1Simon ST, Kini V, Levy AE, Ho PM. Medication adherence in cardiovascular medicine. BMJ 2021; 374: n1493. 10.1136/bmj.n1493 PubMedGoogle Scholar 2Gackowski M, Jasińska-Stroschein M, Osmałek T, Waszyk-Nowaczyk M. Innovative approaches to enhance and measure medication adherence in chronic disease management: a review. Med Sci Monit 2024; 16: e944605. Google Scholar 3Kleinsinger F. The unmet challenge of medication nonadherence. Perm J 2018; 22: 18–033. PubMedGoogle Scholar 4Jackevicius CA, Li P, Tu JV. Prevalence, predictors, and outcomes of primary nonadherence after acute myocardial infarction. Circulation 2008; 117: 1028–1036. 10.1161/CIRCULATIONAHA.107.706820 PubMedWeb of Science®Google Scholar 5Bansilal S, Castellano JM, Garrido E, Wei HG, Freeman A, Spettell C et al. Assessing the impact of medication adherence on long-term cardiovascular outcomes. J Am Coll Cardiol 2016; 68: 789–801. 10.1016/j.jacc.2016.06.005 PubMedWeb of Science®Google Scholar 6Wilhelmsen NC, Eriksson T. Medication adherence interventions and outcomes: an overview of systematic reviews. Eur J Hosp Pharm 2019; 26: 187–192. 10.1136/ejhpharm-2018-001725 PubMedWeb of Science®Google Scholar 7Engel T, Ungar B, Ben-Haim G, Levhar N, Eliakim R, Ben-Horin S. Re-phrasing the question: a simple tool for evaluation of adherence to therapy in patients with inflammatory bowel disease. United European Gastroenterol J 2017; 5: 880–886. 10.1177/2050640616687838 CASPubMedWeb of Science®Google Scholar 8Abegaz TM, Shehab A, Gebreyohannes EA, Bhagavathula AS, Elnour AA. Nonadherence to antihypertensive drugs: a systematic review and meta-analysis. Med (Baltimore) 2017; 96: e5641. 10.1097/MD.0000000000005641 PubMedWeb of Science®Google Scholar 9Cimmaruta D, Lombardi N, Borghi C, Rosano G et al. Polypill, hypertension and medication adherence: the solution strategy? Int J Cardiol 2018; 252: 181–186. 10.1016/j.ijcard.2017.11.075 CASPubMedWeb of Science®Google Scholar 10de Oliveira Costa, J, Lin, J, Pearson, SA et al Persistence and adherence to cardiovascular medicines in Australia. J Am Heart Assoc 2023; 12: e030264 PubMedGoogle Scholar Early ViewOnline Version of Record before inclusion in an issue ReferencesRelatedInformation