解旋酶
RNA解旋酶A
DNA
分子生物学
生物
化学
生物化学
基因
核糖核酸
作者
Wangming Zhang,Xiaojing Yu,Linchun Bao,Tianhui He,Weidong Pan,Pinhao Li,Jinhe Liu,Xiaohua Liu,Liuqi Yang,Jielin Liu
标识
DOI:10.1016/j.biopha.2023.115908
摘要
The high expression of BLM (Bloom syndrome) DNA helicase in tumors involves its strong association with cell expansion. Bisbenzylisoquinoline alkaloids own an antitumor property and have developed as candidates for anticancer drugs. This paper aimed to study the antitumor effect of fangchinoline derivative HY-2 by targeting BLM
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