Erector spinae plane block in dogs undergoing hemilaminectomy: A prospective randomized clinical trial

医学 麻醉 芬太尼 随机对照试验 围手术期 吗啡 左旋布比卡因 入射(几何) 类阿片 外科 止痛药 内科学 光学 物理 受体
作者
Cristiano Bendinelli,Marianna D’Angelo,Fabio Leonardi,Natalí Verdier,Francesca Cozzi,Rocco Lombardo,Diego A. Portela
出处
期刊:Veterinary Anaesthesia and Analgesia [Elsevier BV]
卷期号:51 (3): 279-287 被引量:15
标识
DOI:10.1016/j.vaa.2024.02.002
摘要

To compare the perioperative cumulative opioid consumption and the incidence of cardiovascular complications in dogs undergoing hemilaminectomy in which either an erector spinae plane (ESP) block or systemic opioids were administered.Prospective randomized clinical trial.A total of 60 client-owned dogs.Dogs were randomized to one of three groups: an ESP block (group ESP), a constant rate infusion of fentanyl (group FNT, positive control) or a single dose of methadone as premedication (group MTD, negative control). Intraoperative nociceptive response was treated with fentanyl [1 μg kg-1, intravenously (IV)] boli. Before closure of the surgical site, morphine (0.1 mg kg-1) was applied to the dura mater. The cumulative dose of opioids was recorded and compared between groups. The incidence of intraoperative bradycardia and/or hypotension and the time to extubation were compared between groups. The short form of the Glasgow Composite Pain Scale (SF-GCPS) was used to score nociception before anaesthetic induction and 1, 2, 6, 12,18 and 24 hours postoperatively. Methadone 0.2 mg kg-1 was administered IV if the SF-GCPS score was ≥ 5.Group MTD required more intraoperative rescue analgesia than groups ESP (p = 0.008) and FNT (p = 0.001). The total cumulative intraoperative dose of fentanyl was higher in groups FNT (p < 0.0001) and MTD (p = 0.002) than in group ESP. The incidence of cardiovascular complications was similar between groups. Extubation time was longer in group MTD (p = 0.03). Postoperatively, the time to first rescue analgesia was longer in group ESP than in group MTD (p = 0.03). The cumulative postoperative opioid consumption and pain scores were similar between groups.The ESP block resulted in a reduced intraoperative opioid consumption compared with the control positive and negative groups.
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