S1PR1型
福克斯A1
染色质免疫沉淀
癌症研究
信号转导
小RNA
生物
转录因子
细胞生物学
基因表达
血管内皮生长因子A
基因
发起人
遗传学
血管内皮生长因子受体
血管内皮生长因子
作者
Yanfei Chai,Hong Xiang,Yuchao Ma,Wei Feng,Zhibin Jiang,Qianjun Zhu,Yingji Chen,Quanjun Liu,Jing Zhang,Jie Ouyang,Peng Gao,Xiao Zhang,Shuhua Chen,Longyu Jin,Hongwei Lu
标识
DOI:10.1186/s13046-024-03230-5
摘要
The expression of S1PR1 is downregulated in LUAD, which is positively correlated with prognosis. S1PR1 regulates the malignant function of LUAD cells by inhibiting the expression of COL5A1, MMP1 and SERPINE1 through the p-STAT1/miR-30c-5p/FOXA1 signaling pathway.
科研通智能强力驱动
Strongly Powered by AbleSci AI