Involvement of integument‐rich CYP4G19 in hydrocarbon biosynthesis and cuticular penetration resistance in Blattella germanica (L.)

Our findings confirm that CYP4G19 is involved in hydrocarbon production and appears to contribute to hydrocarbon-based penetration resistance in B. germanica. This study highlights the lipid-based penetration resistance, advancing our understanding of the molecular mechanism underlying P450-mediated cuticular penetration resistance in insects. © 2019 Society of Chemical Industry.