Association of Sleep Variables With Cognitive Performance and the Risk of Dementia in the Sleep and Dementia Consortium

BACKGROUND AND OBJECTIVES: Sleep is multidimensional, and it remains unclear which aspects are most relevant to cognition and dementia risk. We aimed to apply a data-driven approach to identify clusters of sleep variables that reflect meaningful sleep composites and examined their association with cognition and dementia risk. METHODS: < 0.05. RESULTS: = 0.039) were associated with better global cognition. However, no significant associations were identified between the 9 sleep composites and dementia risk. DISCUSSION: Sleep composites were not significantly associated with dementia risk. However, longer, more consolidated sleep and stronger slow oscillation-spindle coupling were associated with cognitive performance. These composites may be useful in guiding further investigations of sleep-brain health relationships.