威尼斯人
奥比努图库单抗
慢性淋巴细胞白血病
氯霉素
医学
内科学
氟达拉滨
伊布替尼
白血病
IGHV@
肿瘤科
苯达莫司汀
免疫学
化疗
环磷酰胺
作者
Kirsten Fischer,Othman Al‐Sawaf,Anna‐Maria Fink,Mark Dixon,Jasmin Bahlo,Simon Warburton,Thomas J. Kipps,Robert Weinkove,Sue Robinson,Till Seiler,Stephen Opat,Carolyn Owen,Javier López,Kathryn Humphrey,Rod Humerickhouse,Eugen Tausch,Lukas P. Frenzel,Barbara Eichhorst,Clemens-M. Wendtner,Stephan Stilgenbauer
出处
期刊:Blood
[Elsevier BV]
日期:2017-03-22
卷期号:129 (19): 2702-2705
被引量:117
标识
DOI:10.1182/blood-2017-01-761973
摘要
To the editor:
In chronic lymphocytic leukemia (CLL), the median age at diagnosis is 72 years, and most patients requiring therapy have coexisting medical conditions. Venetoclax is a potent BH3-mimetic compound that selectively antagonizes BCL-2 and has shown efficacy as monotherapy and with
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