Multi‐shelled Dendritic Mesoporous Organosilica Hollow Spheres: Roles of Composition and Architecture in Cancer Immunotherapy

Abstract Developing potent adjuvants for the stimulation of robust immune response is central for effective cancer immunotherapy. Double‐shelled dendritic mesoporous organosilica hollow spheres are an excellent adjuvant and provide superior immunity in cancer immunotherapy, and better than their counterparts either with a pure silica composition or a single‐walled architecture. This study provides new insights in the rational design of effective nanostructured adjuvants for vaccine developments.