医学
嗅觉缺失
脑病
神经系统
呼吸系统
中枢神经系统
冠状病毒
脑炎
外周神经系统
疾病
重症监护医学
免疫学
内科学
2019年冠状病毒病(COVID-19)
病毒
传染病(医学专业)
精神科
作者
Santosh Singh,Nikita Meher,Arifullah Mohammed,Mohammad Khairul Azhar Abdul Razab,L. V. K. S. Bhaskar,Norazlina Mat Nawi
出处
期刊:Medicine
[Ovid Technologies (Wolters Kluwer)]
日期:2023-02-03
卷期号:102 (5): e30284-e30284
被引量:10
标识
DOI:10.1097/md.0000000000030284
摘要
The primary target of severe acute respiratory syndrome coronavirus 2 is the respiratory system including the nose and lungs, however, it can also damage the kidneys, cardiovascular system and gastrointestinal system. Many recent reports suggested that severe acute respiratory syndrome coronavirus 2 infections can also affect the central nervous system as well as peripheral nervous system that lead to the several neurological complications. The virus can break the blood brain barrier and enters the brain via haematological route or directly by the angiotensin-converting enzyme 2 receptors present on endothelial cells of many cerebral tissues. The neurological complications are manifested by headache, dizziness, encephalopathy, encephalitis, cerebrovascular disease, anosmia, hypogeusia, muscle damage, etc. This review article described the possible routes and mechanism of nervous system infection and the range of neurological complications of COVID-19 that may help the medical practitioners and researchers to improve the clinical treatment and reduce the mortality rate among patients with viral diseases.
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