Intratumoral Microbiome–related MRI Model for Predicting Breast Cancer Shrinkage Pattern Following Neoadjuvant Therapy

< .001), remaining robust across molecular subtypes (AUC range, 0.85-0.91) and tumor stages (AUC range, 0.84-0.89). Shapley additive explanations confirmed that each imaging feature independently predicted TSP. Conclusion An intratumoral microbiome-related MRI model enabled precise TSP prediction. © The Author(s) 2025. Published by the Radiological Society of North America under a CC BY 4.0 license.