Altered thalamic connectivity patterns in pediatric temporal lobe epilepsy: A gradient mapping study

This study identified two key thalamic connectivity patterns in pediatric TLE, revealing heightened thalamic connectivity to mesial temporal regions and to the basal ganglia. Findings suggest an adaptive inhibitory basal ganglia output on thalamo-cortical seizure transmission and the potential predictive value of thalamo-hippocampal connectivity for surgical outcomes.