胺气处理
酯交换
化学
叔胺
有机化学
酒
硫酸盐
功能群
蒸馏
过程(计算)
催化作用
计算机科学
聚合物
操作系统
作者
Ziwei Li,Zeng Hong,Chao Qian,Xinzhi Chen,Shaodong Zhou
标识
DOI:10.1002/chem.202303832
摘要
A novel method to prepare asymmetric amine ethers is reported. Tertiary amine alcohol hydrogen sulfate intermediates are prepared through a reactive distillation process, followed by the transesterification process to afford eventually asymmetric amine ethers. Experiments and DFT calculations revealed the essential roles the sulfate group plays in the highly selective monoesterification process. This clean method is tolerant towards various functional groups with good yields under mild condition, which is obviously superior compared to the conventional processes.
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