Facilely construct of GSH-responsive nanogel by photocrosslinking based on a new multi-functional emulsify-crosslinking agent for comprehensively improved utilization rate of pesticides

The extremely low utilization efficiency of pesticides has driven the development of various smart, green pesticide-delivery systems. However, the existing strategies for controlling pesticide losses are step-specific or complicated preparation processes. Here, by precisely designing a multifunctional emulsify-crosslinking agent (PFTA) and innovating drug loading means, we constructed a simple and compatible nanogel delivery system by photocrosslinking, realizing the comprehensive improvement of pesticide efficiency in terms of encapsulation, deposition, retention, photodegradation resistance and release of pesticides. The nanosized networks can effectively and firmly encapsulate pesticides and protect pesticides from photodegradation, 82.42 % of the loaded AVM remained in the nanogel after UV irradiation for 28 h. Meanwhile, the chain structure of PTFA and nanosize network ensure nanogel complete deposition on superhydrophobic plant surfaces and inhibition of rainwater erosion. More importantly, glutathione-induced disruption of the nanosized networks determines the precise pesticide release. Our findings provide new insight into and new directions for the study of novel agrochemical-delivery systems.