传输(电信)
乙型肝炎病毒
病毒学
基本再生数
人口
年龄结构
生物
乙型肝炎
病毒
医学
免疫学
计算机科学
电信
环境卫生
作者
Lan Zou,Shigui Ruan,Weinian Zhang
出处
期刊:Siam Journal on Applied Mathematics
[Society for Industrial and Applied Mathematics]
日期:2010-11-04
卷期号:70 (8): 3121-3139
被引量:42
摘要
Hepatitis B virus (HBV) infection is endemic in many parts of the world. One of the characteristics of HBV transmission is the age structure of the host population. In this paper, we propose an age-structured model for the transmission dynamics of HBV. The host population is stratified by age and is divided into six subclasses: susceptible, latently infected, acutely infectious, carrier, recovered, and vaccinated individuals. By determining the basic reproduction number, we study the existence and stability of the disease-free and endemic steady state solutions of the model. Numerical simulations are performed to find optimal strategies for controlling the transmission of HBV.
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