噬菌体疗法
药品审批
噬菌体
生物技术
生物
药品
药理学
遗传学
大肠杆菌
基因
作者
Wessam A. Sarhan,Hassan M.E. Azzazy
标识
DOI:10.1586/14787210.2015.990383
摘要
Bacterial resistance is not only restricted to human infections but is also a major problem in food. With the marked decrease in produced antimicrobials, the world is now reassessing bacteriophages. In 2006, ListShield™ received the US FDA approval for using phage in food. Nevertheless, regulatory approval of phage-based therapeutics is still facing many challenges. This review highlights the use of bacteriophages as biocontrol agents in the food industry. It also focuses on the challenges still facing the regulatory approval of phage-based therapeutics and the proposed approaches to overcome such challenges.
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