Total synthesis of naturally occurring (+)-psychotriasine and the related tetrahydro-β-carboline, dimeric tryptamines with NC connectivities

Naturally occurring (+)-psychotriasine (+)-1 and congener tetrahydro-β-carboline (+)-3, which are dimeric tryptophan-derived alkaloids with tryptamine and carboline units connected by the indole nitrogen to the quaternary carbon atom of the pyrrolidinoindoline core, have been synthesized for the first time and their absolute configurations confirmed.