Three cases of Major Aphthous Stomatitis (Sutton’s Disease)

Major aphthous stomatitis is one of the recurrent aphthous stomatitis(RAS), and about 10% of RAS is major aphthous stomatitis. The diameter of the wheal of the major aphthous stomatitis is more than lcm. The ulcer can be developed in any part of oral mucosa and usually it is healed with or without scar after 10∼30 days. Frequently major aphthous stomatitis is confused with oral malignancy due to large scale of ulcer and severe scarring process, therefore biopsy can be needed to distinguish with cancer and carefully observed. So authors introduce 3 cases of major aphthous stomatitis with literature review.