The health issues are one part of global problems in this world that must be resolved. This issue provides an opportunity for elements of the international community to participate in improving and building global health conditions. This provides for state actors and NGO’s to work synergize in global issues, especially in health sector. It can be seen from the various hazard caused by natural and non-natural disasters. Therefore, in the international relations perspective health issues as having significant to be solved involving global stakeholders. Keywords: global security, global health, international relations, NGO