177 Lu-PSMA靶向治疗转移性去势抵抗性前列腺癌的研究进展

Prostate cancer is one of the most common malignancies worldwide. Many advances have been made over the past years, but the treatment of metastatic prostate cancer remains challenging. In many cases, existing therapies have become ineffective for controlling tumor progression. Thus, new approaches are urgently needed. Radioligand therapy with 177Lu-Prostate specific membrane antigen (PSMA) is an innovative and effective therapy for patients with castrationresistant metastatic prostate cancer. PSMA is expected to be a standard regimen for prostate cancer as it is well tolerated by patients and has high potential for improving overall survival. Key words: Prostate-specific membrane antigen; Prostatic neoplasms; Molecular targeted therapy; Metastatic castration resistant prostate cancer; 177Lu