Proceedings of the International Symposium on Subtypes of Muscarinic Receptors 2 (2nd) Held in Boston, Massachusetts on August 22-24 1985

Abstract : Partial contents: The molecular basis of receptor selectivity; Biochemical studies on muscarinic receptors in porcine atrium; Muscarinic receptor subclasses: The binding properties of the soluble receptor binding sites; Characteristics of two biochemical responses to stimulation of muscarinic cholinergic receptors; Muscarinic receptors and membrane ion conductances; Muscarinic receptors in the submucous plexus and their roles in mucosal ion transport; A mechanism of muscarinic excitation in dissociated smooth muscle cells; In-vivo labelling of peripheral muscarinic receptors; Modulation of muscarinic receptors and their interactions; The cholinergic hypothesis of dementia; Biochemical and functional basis of putative muscarinic receptor subtypes and its implications; Mapping of subtypes of muscarinic receptors in the human brain with receptor autoradiographic techniques; Inositol lipids and signal transduction at CNS muscarinic receptors; Mechanisms of muscarinic excitatory synaptic transmission in ganglia and brain; Pirenzepine discriminates among ionic responses to acetylcholine in guinea-pig cerebral cortex and reticular nucleus of thalamus. Keywords: Pharmacological antagonists, Binding sites, Alzheimers disease, Drugs, Pharmacological agonists.