Tumor response from durvalumab (MEDI4736) + tremelimumab treatment in patients with advanced non-small cell lung cancer (NSCLC) is observed regardless of PD-L1 status
作者
Naiyer A. Rizvi,Jamie E. Chaft,Ani Sarkis Balmanoukian,Sarah B. Goldberg,Rachel E. Sanborn,Keith E. Steele,Marlon C. Rebelatto,Yu Gu,Joyson Karakunnel,Scott Antonia
Meeting abstracts As single agents, durvalumab (MEDI4736), a human IgG1 anti-PD-L1 antibody, and tremelimumab, a human IgG2 anti-CTLA-4 antibody, have shown acceptable safety profiles and antitumor activity. Similar to other anti-PD-L1/anti-PD-1 monotherapies, durvalumab has shown greater objective