芳香烃受体
斑马鱼
心脏毒性
小桶
全氟辛烷
生物
功能(生物学)
细胞生物学
基因
化学
遗传学
转录因子
转录组
基因表达
有机化学
钠
化疗
磺酸盐
作者
Honghong Chen,Wenhui Qiu,Xuanjun Yang,Fangyi Chen,Jiaying Chen,Liang Tang,Hanbing Zhong,Jason T. Magnuson,Chunmiao Zheng,Elvis Genbo Xu
标识
DOI:10.1021/acs.est.1c08875
摘要
-morpholino knock-down, uncovering a seminal role of AHR in PFOSA-induced cardiotoxicity. Our results provide the first evidence in fish that PFOSA can impair proper heart development and function and raises concern for PFOSA analogues in the natural environment.
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