Intraosseous papillary intralymphatic angioendothelioma (PILA): one new case and review of the literature

Papillary intralymphatic angioendothelioma (PILA) is a locally aggressive, rarely metastasizing vascular tumor, generally occurring in the soft tissues, with less than 40 cases described in the literature and only three cases reported in bone.We describe the case of a 51-year-old male with an intraosseous PILA of the proximal edge of his left clavicle and two other lesions evident on imaging. The patient was treated with marginal resection of the clavicle lesion but was lost to follow-up 1 month after surgery.PILA can also occur in bone, albeit very rarely, and has to be considered in the differential diagnosis of vascular bone tumors.