非布索坦
别嘌呤醇
痛风
医学
黄嘌呤氧化酶抑制剂
黄嘌呤氧化酶
尿酸
高尿酸血症
嘌呤
药理学
内科学
生物化学
酶
化学
作者
William Β. White,Kenneth G. Saag,Michael A. Becker,Jeffrey S. Borer,Philip B. Gorelick,Andrew Whelton,Barbara Hunt,Majin Castillo,Lhanoo Gunawardhana
标识
DOI：10.1056/nejmoa1710895
摘要
Cardiovascular risk is increased in patients with gout. We compared cardiovascular outcomes associated with febuxostat, a nonpurine xanthine oxidase inhibitor, with those associated with allopurinol, a purine base analogue xanthine oxidase inhibitor, in patients with gout and cardiovascular disease.
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