福克斯O1
叉头转录因子
生物
癌症研究
生物信息学
计算生物学
转录因子
遗传学
基因
作者
Shuai Jiang,Li Tian,Zhi Yang,Wei Hu,Yang Yang
摘要
Neoplasms constituted an enormous burden and contributed to an estimated 8.2 million deaths in 2012 worldwide. FOXO1 (forkhead box O1), a member of the forkhead box (FOX) family, is a transcriptional factor involved in diverse cellular functions. Herein, we concentrate on recent studies of the antineoplastic roles of FOXO1 in neoplasms. This article may serve as a guide for future research and identify FOXO1 as a potent therapeutic target in neoplasms.
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