Detection of lymphocyte proliferation stimulated by HGXPRT protein of Plasmodium falciparum

Objective To determine the effect of proliferation of lymphocytes stimulated by Plasmodium falciparum HGXPRT protein. Methods Lymphocytes from BALB/c mice immunized with Plasmodium falciparum HGXPRT protein were prepared and the proliferation of lymphocytes was determined by CCK-8 after jointly cultured with corresponding stimulators. Results Effects of stimulation depended on the concentration of Plasmodium falciparum HGXPRT and the concentration of 5μg/ml was the most efficacious for the proliferation of lymphocytes. Conclusion Plasmodium falciparum HGXPRT can stimulate the proliferation of lymphocytes.