Objective To investigate the effects of three blind positioning methods of left-sided double-lumen endobronchial tube intubation. Methods One hundred and five patients whose needed general anesthesia with left-sided doublelumen endobronchial intubation in thoracic surgery were enrolled in this study,they were divided into 3 groups according to the random number table,with 35 cases in each group. The anterogade catheterization was conducted with observation on bronchial balloon pressure to perform left-side endobronchial tube intubation in the balloon pressure group,the catheterization was conducted with the method of tube resistance in the tube resistance group,and the catheterization was conducted by predicting the depth of endobronchial tube according to the patient' s body height in the body height prediction group. The completed rates and the time consumptions for separate lung in the first attempt,the accuracy and complications of three groups were compared. Results The completed rates for separate lung of balloon pressure group,tube resistance group and body height prediction group were 91. 43%,62. 86%,65. 71%,respectively,the time consumptions were( 103.23 ±13.02) seconds,( 114.66 ±26.54) seconds,( 83. 57 ±35. 77) seconds,respectively. The positive predictive value of accuracy were 0. 91,0. 59,0. 65,respectively. The accuracy of balloon pressure group was significantly higher than that of tube resistance group and body height prediction group( P 0. 05),but there was no significant difference in the accuracy between tube resistance group and body height prediction group( P 0. 05). The incidences of mucosal bleeding,hoarse showed no significant difference among three groups( P 0. 05). Conclusion The effect of visual bronchial balloon pressure method is better than that of tube resistance method and body height prediction for left-sided endobroncial intubation.