A convenient one-pot synthesis and bioactivity of N -dichloroacetyl-5-aryl-1,3-oxazolidines

Abstract New N -dichloroacetyl-5-aryl-1,3-oxazolidines 4 were synthesized by cycloaddition reaction of an aryl substituted hydroxyalkylamine 1 with aldehyde or ketone 2 , followed by acylation, without isolation of the intermediate product 3 . The structures of compounds 4 were determined by spectral and elemental analyses. The structure of 4b was determined by an X-ray crystallographic analysis. The bioassay results demonstrate that these compounds could alleviate chlorsulfuron injury to maize.