Study on Synthesis and Structure Identification of Terpenyl Gallates

A synthetic route of terpenyl gallates was advanced.Gallic acid was acetylated to form 3,4,5-triacetoxybenzoic acid at first,3,4,5-triacetoxybenzoic acid was esterified with six terpenyl alcohols such as farnesol,geraniol,linalool,nerolidol,menthol,and hydroabietyl alcohol by N,N′-dicyclohexyl carbodiimide(DCC) with the assistance of ultrasound at room temperature to produce terpenyl 3,4,5-triacetoxybenzates,respectively.The terpenyl 3,4,5-triacetoxybenzates were then deacetylated by hydrazine hydrate to produce corresponding terpenyl gallates.The total yield of farnesyl gallate,geranyl gallate,linalyl gallate,nerolidyl gallate,menthyl gallate,and hydroabietyl gallate were 86.17%,85.26%,76.32%,87.50%,79.22% and 82.54%,respectively.The synthetic method had advantages of low reaction temperature,short reaction time,and high conversion rate.The chemical structures of above six terpenyl gallates were identified at last.