Progress in anti-angiogenesis cancer therapy and anti-angiogenesis drugs

OBSTRACTIVE To introduce mechanism of anti-angiogenesis cancer therapy and recent advances in anti-angiogenesis drugs.METHOD Settle and conclude according to the relevant domestic and international literature.RESULTS Growth factors,lytic enzymes and inflammatory cells were main molecular mediators in cancer angiogenesis and were proved to be target of many natural or synthetic chemically molecules in cancer therapy.CONCLUSION The development of anti-angiogenesis drugs can be a promising approach for the treatment of tumor.