SENSE and Compressed SENSE chemical shift encoded multi-gradient echo for T2* quantification in the liver

T2*, measured using 3D breath-hold chemical shift encoded multi-gradient echo can be used to estimate liver iron concentration. The breath-hold duration (typically 10-20 s) with traditional parallel imaging acceleration techniques such as Sensitivity Encoding (SENSE) can be difficult for patients. Compressed SENSE (C-SENSE) can be used to decrease acquisition time. We compare T2* obtained with SENSE and C-SENSE in 21 patients. We found that C-SENSE acquisition was faster (9 s vs 18 s), with strong correlation and agreement with SENSE. Our findings suggest C-SENSE may potentially improve patient tolerance and turnover speed for T2* acquisitions when compared to SENSE.