凝聚
自愈水凝胶
生物相容性材料
化学
软物质
弹性体
纳米技术
机器人
毛细管作用
适应性
磁场
化学工程
材料科学
生物医学工程
计算机科学
复合材料
高分子化学
工程类
人工智能
色谱法
胶体
有机化学
物理
生态学
量子力学
生物
作者
Pengchao Zhao,Fuyang Qu,Hao Fu,Jianyang Zhao,Jiaxin Guo,Jian Xu,Yi‐Ping Ho,Michael K. Chan,Liming Bian
摘要
Developing magnetic ultrasoft robots to navigate through extraordinarily narrow and confined spaces like capillaries in vivo requires synthesizing materials with excessive deformability, responsive actuation, and rapid adaptability, which are difficult to achieve with the current soft polymeric materials, such as elastomers and hydrogels. We report a magnetically actuatable and water-immiscible (MAWI) coacervate based on the assembled magnetic core-shell nanoparticles to function as a liquid robot. The degradable and biocompatible millimeter-sized MAWI coacervate liquid robot can remain stable under changing pH and salt concentrations, release loaded cargoes on demand, squeeze through an artificial capillary network within seconds, and realize intravascular targeting in vivo guided by an external magnetic field. We believe the proposed "coacervate-based liquid robot" can implement demanding tasks beyond the capability of conventional elastomer or hydrogel-based soft robots in the field of biomedicine and represents a distinct design strategy for high-performance ultrasoft robots.
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