多糖
壳聚糖
药物输送
生物相容性
化学
纳米技术
生物技术
生化工程
材料科学
生物
生物化学
有机化学
工程类
作者
Rabab Fatima,Mousmee Sharma,Parteek Prasher,Sachin Kumar Singh,Dinesh Kumar Chellappan,Indu Pal Kaur,Kamal Dua
标识
DOI:10.1002/slct.202300941
摘要
Abstract The pressing need for the development of diversified and non‐toxic biomaterials in recent decades has led to the emergence of novel and valuable structural modifications in polysaccharides to broaden their spectrum of applications. Polysaccharides are macromolecules with multifaceted diverse structures and exhibit wide range of pharmacological and biological activities. Naturally occurring polysaccharides such as starch, chitosan, alginate, acetalated dextran and pectin could potentially negate major concerns associated with the selection of suitable polysaccharides without compromising their unique bioactive nature. Chemical modification of polysaccharides offers distinctive benefits such as improved biocompatibility, stability, solubility, and functionality making them more valuable for a variety of biomedical applications such as drug delivery, gene delivery, cell culture technology and tissue engineering. The present review is a compendium of relevant chemically modified polysaccharides and discusses their role in diverse fields of pharmacy and medicine.
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