Abstract This paper presents a potential condition to separate kaolinite through flotation when it is present in bauxite ore. This research anticipates a Brazilian industry require -ment, considering the tendency towards the need for aluminosilicates removal from bauxite ores, as has already occurred in China. Kaolinite is the most abundant alumi-nosilicate, and gibbsite is the main aluminum bearing mineral in Brazilian bauxite ores.The first step was a fundamental study involving microflotation experiments with pure samples of kaolinite and gibbsite. Ammonium quaternary salts and amines were used as the collector and corn starch as the depressant.In a fundamental study, the best conditions determined in the first step were evaluated for the flotation of kaolinite from bauxite ore using laboratory scale ex-periments. Tests with AQ142/starch (pH 10) and CTAB (pH 7) led to satisfactory results. In general, the highest values of alumina/silica mass ratio were obtained with AQ142/starch and the highest values of mass recovery and metallurgical recovery were achieved with CTAB.