钯
荧光
炔烃
化学
检出限
水介质
催化作用
反应性(心理学)
组合化学
水溶液
纳米技术
光化学
材料科学
生物化学
有机化学
色谱法
医学
病理
物理
替代医学
量子力学
作者
Fangjun Huo,Yaqiong Zhang,Jin Soo Kang,Jianbin Chao,Yongbin Zhang,Caixia Yin
标识
DOI:10.1016/j.snb.2016.11.034
摘要
Palladium is significant in chemistry, biology and environmental science, while as a toxic metal, it could have adverse effects on our health and the environment. It is thus critical to monitor the changes of Pd (II) in living cells. Here, we developed a new colorimetric and fluorometric probe (TP1) based on palladium(II)-involved reactivity. Compared with the reported Pd (II) sensors, TP1 was the first alkyne compound fluorescent probe with excellent water-solubility for Pd2+, which was via catalytic-depropargylation to form oxime for the detection of Pd2+ within a rapid response time 80 s. The detection limit of TP1 toward Pd(II) was estimated as 0.47 μM. In addition, the ability of the TP1 to detect Pd(II) in living cells (HepG2 cells) has been also proven. These results indicated that TP1 was a highly sensitive turn-off Pd(II) dye with promising biological applications.
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