Non-alcoholic fatty liver disease is a recent rapid spread chronic complications along with the rapid development of diabetes. In type 2 diabetes patients, about 50% to 75% of patients associated with non-alcoholic fatty liver, and who combined non-alcoholic fatty liver is more prone to cardiovascular disease, his risk is greater. Now, more recognize on the non-alcoholic fatty liver mechanism is that two hits theory and in this process, insulin resistance played a crucial role. Current diagnosis of non-alcoholic fatty liver disease in diabetics rely mainly on type-b ultrasonic.Treatment of this disease remains a major problem,more effective methods include lifestyle adjustments and the use of insulin-sensitizing agents.