Through the study on the relationship between the parasites and the host and their effective factors,the authors find that,different kinds of parasites have different affinity and can parasitize in different organs and tissues of host. In the period of infection caused by two or more than two kinds of parasite, the parasite versus host reaction (PVHR),mechanical trauma, malnutrition allergic reaction etc. will emerge with the interaction of the above parasites. On the other hand, in order to eliminate invasive parasite and establish immunity to parasite, a series of immune reaction appear in the host.